Job Description

Director-Gene Therapy Drug Discovery Biologist

Join to apply for the Director-Gene Therapy Drug Discovery Biologist role at Solid Biosciences

Continue with Google Continue with Google

Director-Gene Therapy Drug Discovery Biologist

Join to apply for the Director-Gene Therapy Drug Discovery Biologist role at Solid Biosciences

This range is provided by Solid Biosciences. Your actual pay will be based on your skills and experience talk with your recruiter to learn more.

Base pay range

$200,000.00/yr - $230,000.00/yr

Job Title

Director Gene Therapy Drug Discovery Biologist

Reports To (title)

Senior Director, Molecular Therapeutics-Scientific Lead

Solid Summary

Solid Biosciences is a life science company focused on advancing a portfolio of neuromuscular and cardiac programs, including SGT-003, a differentiated gene therapy candidate for the treatment of Duchenne, SGT-401, a gene therapy program for the treatment of BAG3 mediated dilated cardiomyopathy, SGT-212, a gene therapy program for the treatment of Friedreichs Ataxia, and additional assets for the treatment of fatal cardiac diseases. Solid aims to be the center of excellence across a given disease spectrum bringing together those with expertise in science, technology, disease management, and care. Patient-focused and founded by those directly impacted, Solids mandate is to improve the daily lives of patients living with these devastating diseases.

Position Summary

We are seeking a highly skilled and motivated PhD scientist to join the Molecular Therapeutics team to select our lead therapeutics. The ideal candidate will have a strong scientific background in human iPSC biology, in vivo biodistribution studies (small and large animal), protein science, molecular biology, and quantitative imaging techniques.

Key Duties & Accountabilities

• Contribute to both the inception and selection of AAV libraries
• Optimize in vitro and in vivo models to select lead therapeutics for translation to humans
• Lead a scientific team to quantitatively compare VG, mRNA, and protein levels
• Detailed understanding of antibody and FISH imaging techniques to quantify biodistribution and expression levels
• Collaborate within the MTx Department and across the R&D organization to incorporate selected therapies into the Discovery & Translational Development pipeline
• Manage projects with outside partners from inception to completion
• Communicate findings and insights to stakeholders through presentations, patents, publications, and scientific conferences

Core Competencies Required

• Strong track record in experimental design, molecular genetics and cellular biology, statistics, protein science, and imaging
• Leadership experience in a biotechnology/pharmaceutical company focusing on biologics drug discovery
• Proficiency in computing include Geneious, Endnote, BLAST, Ensembl, NCBI, Uniprot, UCSC, GTEx, Microsoft, PRISM statistics program, Benchling
• Strong problem-solving skills and the ability to work independently and collaboratively
• Excellent communication and presentation skills

Knowledge: Education, Experience, & Skills:

PhD in physiology/pharmacology, Post-Doctorate in vector biology preferred, with >3 years industry experience leading laboratory scientists

Travel Commitment

Solid Biosciences, Charlestown, MA

Role Location

(HQ, Hybrid, Remote, NC, etc.)

HQ

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Other

Referrals increase your chances of interviewing at Solid Biosciences by 2x

Get notified about new Director jobs in Boston, MA .

Vice President, Delivery Lead, Strategic Services

Boston, MA $125,000 - $150,000 2 weeks ago

Greater Boston $160,000 - $200,000 4 weeks ago

Newtonville, MA
$140,000.00
-
$175,000.00
2 days ago

Vice President/Senior Vice President, Head of Program Development

Boston, MA
$179,008.00
-
$270,000.00
4 days ago

Boston, MA
$149,133.00
-
$195,000.00
4 days ago

Boston, MA
$200,000.00
-
$240,000.00
2 weeks ago

Head of Strategic Transformation Executive Vice President

Boston, MA
$300,000.00
-
$412,500.00
3 days ago

Head of Strategic Transformation Executive Vice President

Boston, MA
$300,000.00
-
$412,500.00
3 days ago

Senior Vice President / Partner, Product R&D - Partnering Strategy & Operations

Associate Director/Director, Project Management

Vice President of Public Affairs & Executive Director of the Planned Parenthood Advocacy Fund of Massachusetts (PPAF)

Were unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

#J-18808-Ljbffr

Job Tags

Full time, Remote work,

Similar Jobs